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Welcome! My name is William Li, and I am an MD-PhD student at Harvard working with Xiaowei Zhuang on developing 3D-genome imaging approaches to study the human brain. I studied physics and computer science as an undergraduate at MIT, where I pursued research with Marin Soljačić, Steven Johnson, and Manolis Kellis. My work focuses on combining advanced imaging and computational methods to study the biological mechanisms underlying neurological disease.

You can learn more about my work on the Research page and view my published papers under Publications. For more about me, please see my CV, Google Scholar, and LinkedIn. Feel free to reach out by email if you would like to get in touch.

Selected publications

*corresponding author
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Transcending shift-invariance in the paraxial regime via end-to-end inverse design of freeform nanophotonics.
In Optics Express, 2023.
We present a method for the nanophotonic inverse design of compact imaging systems whose resolution is not constrained by paraxial shift-invariance. Our design is done end-to-end, integrating density-based full-Maxwell topology optimization with a fully iterative elastic-net reconstruction algorithm.